- Call for 2 postdoc positions in European grant “SPARC-AD”
Title of the project: Integrating multimodal, multiscale imaging and artificial intelligence for early amyloid
detection in their native environment
2x Postdoctoral researchers (up to 7 years after PhD degree)
Duration: 3 years (36 months) each position
Salary: 2692 €/month (equivalent paid in Polish zloty, PLN)
Project partners : Sweden, Canada, Germany, Becker, Poland,
Contact info: Prof Aleksandra Szczepankiewicz, Head of Experimental Medicine Centre, Poznan University of Medical
Summary of the project
Our current understanding on molecular mechanisms that determine early Alzheimer’s disease (AD) progression is very limited. Amyloids start to build up decades before the onset of the first disease symptoms. Thus, there is a need for their early detection. We propose an interdisciplinary project that aims to characterize molecular structures directly in their native environments. Using our multimodal molecular imaging approach, we will identify pathological types of amyloids and resolve their structures. The main methodological breakthrough is the implementation of artificial intelligence (AI) as a powerful tool for mining complex spectroscopic data and uncovering spatiotemporal patterns that may detect early (subtle) structural changes. The anticipated results on amyloid structures resolved directly in cells and tissues will be used for the development of new tracers for early diagnostic and effective anti-amyloid interventions. The consortium’s specific goals are as follows: i) By combining multimodal structural imaging with AI, we aim to develop a comprehensive framework for deep molecular profiling of heterogenic samples like brain tissue; ii) Investigate the relationship between amyloid structure and toxicity using a modeling approach; iii) Explore the formation of amyloid in living systems. Experimental work will involve not only APP mice but also human AD organoids, adding a substantial translational aspect to our research. The strong complementarity within the consortium allows for the design of streamlined multidimensional work packages, ensuring swift progression with mutual contributions from consortium members at each project step. Importantly, our consortium is highly inclusive, gender-equal, and transnational, promoting strong European integration, data, and skill transfer. Collaboration among consortium members via joint supervision of PhD students will be essential at every project stage, with significant mobility of young researchers expected to be a key feature.
Keywords: Early amyloid detection; Molecular profiling; Multimodal analysis; Artificial intelligence; Deep learning
- Post-Doctoral position – University of Sorbonne
- Brain Conference Registration open! – Fodele Beach 27—30 Oct 2025
Towards an integrated understanding of the dynamics of mental health and stress resilience as adaptation to uncertainty across multiple nested timescales
Mental health depends on our ability to adapt our brain, mind and decisions flexibly to the uncertainty of our constantly changing environment. Such adaptation occurs over several nested timescales: within an individual’s lifetime through both rapid learning and longer-term developmental plasticity, and between generations through the transfer of adaptive traits. Yet we have little understanding of the basic principles of healthy adaptation to uncertainty for stress resilience.
This Brain Conference will bring together a unique and interdisciplinary group of internationally recognised experts in evolutionary biology, computational cognitive neuroscience, developmental psychology, systems neuroscience, genetics/epigenetics and clinical psychiatry, to promote synthesis and synergy between the computational, social and life sciences to advance knowledge about the adaptive mind.
- Post Doc position at the Wisconsin National Primate Research Center
The Saalmann Lab (https://saalmannlab.psych.wisc.edu/) at the Wisconsin National Primate Research Center, in partnership with the Panagiotaropoulos Lab (https://en.psych.uoa.gr/faculty_en/theofanis_panagiotaropoulos) at the University of Athens, is seeking to hire a postdoctoral researcher to investigate the neural basis of consciousness. The research is funded by the Templeton World Charity Foundation (https://www.templetonworldcharity.org/blog/testing-gnw-and-iit-through-animal-models) and the position is based at the University of Wisconsin – Madison.
The successful candidate will join a multi-disciplinary team, using a range of electrophysiology, neuroimaging, causal manipulation and computational methods, including Neuropixels recordings and brain stimulation during visual perception tasks. This will involve collaboration with scientists from the Allen Institute for Brain Science, Sorbonne University, and University of Pennsylvania.
For inquiries, please contact Dr. Yuri Saalmann (saalmann@wisc.edu) and Dr. Fanis Panagiotaropoulos (fpanag@psych.uoa.gr). - HSfN 2025 Meeting Schedule & Abstract Book now available!